Sometimes it is not easy to disable/enable touchpad on a laptop running Linux. Certainly that was the case for my new Dell XPS. So, here is what I came up with to make my life easier:

To disable all touchpad devices:

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xinput list | grep -i touchpad | \
  awk '{print $6}' | awk -F '=' '{print $2}' | \
  xargs -rn 1 -I {} xinput --disable {}

To enable all touchpad devices:

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xinput list | grep -i touchpad | \
  awk '{print $6}' | awk -F '=' '{print $2}' | \
  xargs -rn 1 -I {} xinput --enable {}

It might then be a good idea to wrap these commands into simple bash -c "<cmd>" and map it to global hotkeys.